That's just east of Quince Road.
According to St. Joseph County Police, an eastbound tow truck had stopped on State Road 2 in order to turn left.
A van rear-ended a Honda Civic, which pushed a Chevy Cruze into the side of the road.
The Civic then hit then the tow truck.
The drivers of the van and Civic were taken to the hospital.
Two kids from the Cruze were checked out on scene, but they were also then taken to the hospital.
Two other drivers were either uninjured or treated at the scene.
The vehicles were removed shortly before 2:30 p.m., and traffic began to flow again.
We'll update this story once we learn more about the severity of the injuries.